Skip to main content

Marc A. LeBeau, Ph.D., F-ABFT

Adjunct professor
Department of Pathology

Education

Doctor of Philosophy
Toxicology, University of Maryland - Baltimore

Master of Science
Forensic science, University of New Haven

Bachelor of Science
Chemistry, criminal justice; Central Missouri State University

Practice Areas

  • Forensic toxicology

Publications and Media Placements

Peer-Reviewed Journals

  1. LeBeau, M., et al. Recommendations for the Toxicological Investigations of Drug-Facilitated Sexual Assaults. Journal of Forensic Sciences, Volume 44, Number 1, January 1999.
  2. LeBeau, M. Toxicological Investigations of Drug-Facilitated Sexual Assaults. Forensic Science Communications, Volume 1, Number 1, 1999.
  3. Schwartz, R., Milteer, R., LeBeau, M. Drug-Facilitated Sexual Assault (Date Rape). Southern Medical Journal, Volume 93, Number 6, 2000.
  4. LeBeau, M., Montgomery, M., Wagner, J., and Miller, M. Analysis of Biofluids for Flunitrazepam and Metabolites by Electrospray Liquid Chromatography/Mass Spectrometry. Journal of Forensic Sciences, Volume 45, Number 5, 2000.
  5. LeBeau, M., Montgomery, M., Miller, M., and Burmeister, S. Analysis of Biofluids for Gamma Hydroxybutyrate (GHB) and Gamma-Butyrolactone (GBL) by Headspace GC/FID and GC/MS. Journal of Analytical Toxicology, Volume 24, 2000. https://doi.org/10.1093/jat/24.6.421
  6. LeBeau, M., Miller, M., and Levine, B. Effect of Storage Temperature on Endogenous GHB Levels in Urine. Forensic Science International, Volume 119(2), 2001. https://doi.org/10.1016/s0379-0738(00)00426-6
  7. Darby, S., Miller, M., Allen, R., and LeBeau, M. A Mass Spectrometric Method for Quantitation of Insulin in Blood Samples. Journal of Analytical Toxicology, Volume 25, 2001. https://doi.org/10.1093/jat/25.1.8
  8. LeBeau, M.A. Forensic Toxicology at the FBI Laboratory. NEACT Journal, Volume 20, Number 1, 2001.
  9. LeBeau, M.A., Montgomery, M.A., Schaff, J.E., and Quenzer, C.F. Fentanyl in Human Hair by Liquid Chromatography Tandem Mass Spectrometry. Anaales de Toxicologie Analytique, 2002.
  10. LeBeau, M.A., Christenson, R.H., Levine, B., Darwin, W.D., and Huestis, M.A. Intra- and Interindividual Variations in Urinary Concentrations of Endogenous Gamma-Hydroxybutyrate (GHB), Journal of Analytical Toxicology, Volume 26, 2002. https://doi.org/10.1093/jat/26.6.340
  11. LeBeau, Marc A., Quality Assurance Guidelines for Laboratories Performing Forensic Analysis of Chemical Terrorism, Forensic Science Communications, Volume 6, Number 2, 2004.
  12. Montgomery, Madeline A., LeBeau, Marc A., Miller, Mark L., and Jufer, Rebecca A. The Identification of Mivacurium and Metabolites in Biological Samples. Journal of Analytical Toxicology, Volume 29, 2005. https://doi.org/10.1093/jat/29.7.637
  13. Montgomery, M.A., LeBeau, M.A., Jenkins, A.J. Qualitative Identification of Doxacurium and its Breakdown Products in Postmortem Fluids by Liquid Chromatography-Tandem Mass Spectrometry. Journal of Analytical Toxicology, Volume 30, 2006. https://doi.org/10.1093/jat/30.1.57
  14. LeBeau, M.A. Montgomery, M.A., Morris-Kukoski, C., Schaff, J.E., Deakin, A., Levine, B., A Comprehensive Study on the Variations of Urinary Concentrations of Endogenous GHB, Journal of Analytical Toxicology, Volume 30, 2006. https://doi.org/10.1093/jat/30.2.98
  15. Jagerdeo, E., Leibowitz, J.N., Schumacher, L., Henningsen, D.A., and LeBeau, M. Analysis of Trace Amount of Bank Dye and Lachrymators from Exploding Bank Devices by Solid-Phase Microextraction and Gas Chromatography-Mass Spectrometry, Journal of Chromatographic Science, Volume 44, 2006. https://doi.org/10.1093/chromsci/44.2.86
  16. Bradley, M.J., Keagy, R.L., Lowe, P.C., Rickenbach, M.P., Wright, D.M., and LeBeau, M.A. A Validation Study for Duct Tape End Matches, Journal of Forensic Sciences, Volume 51, Number 3, May 2006. https://doi.org/10.1111/j.1556-4029.2006.00106.x
  17. LeBeau, M. Montgomery, M., Morris-Kukoski, C., Schaff, J., and Deakin, A. Further Evidence of In Vitro Production of GHB in Urine Samples, Forensic Science International, Volume 169, 2007. https://doi.org/10.1016/j.forsciint.2006.08.007
  18. Morris-Kukoski, C.L., Jagerdeo, E., Schaff, J.E., LeBeau, M.A. Ethanol Analysis from Biological Samples by Dual Rail Robotic Autosampler; Journal of Chromatography B, Volume 850 (2007). https://doi.org/10.1016/j.jchromb.2006.11.034
  19. LeBeau, M. Guidance for Improved Detection of Drugs Used to Facilitate Crimes. Therapeutic Drug Monitoring, Volume 30, Number 2, April 2008. https://doi.org/10.1097/ftd.0b013e31816791d7
  20. Jagerdeo, E., Montgomery, M.A., LeBeau, M.A., and Sibum, M. An Automated SPE/LC/MS/MS Method for the Analysis of Cocaine and Metabolites in Whole Blood; Journal of Chromatography B, Volume 874 (2008). https://doi.org/10.1016/j.jchromb.2008.08.026
  21. Jagerdeo, E., Montgomery, M.A., Sibum, M., Sasaki, T.A., and LeBeau, M.A. Rapid Analysis of Cocaine and Metabolites in Urine Using a Completely Automated Solid-Phase Extraction-High-Performance Liquid Chromatography-Tandem Mass Spectrometry Method; Journal of Analytical Toxicology, Volume 32, Number 8, (2008). https://doi.org/10.1093/jat/32.8.570
  22. Jagerdeo, E., Schaff, J.E., Montgomery, M.A., and LeBeau, M.A. A Semi-Automated Solid Phase Extraction Liquid Chromatography/Tandem Mass Spectrometry Method for the Analysis of Tetrahydrocannabinol and Metabolites in Whole Blood; Rapid Communications in Mass Spectrometry, Vol 23, No. 17 (2009). https://doi.org/10.1002/rcm.4174
  23. LeBeau, M.A. and Montgomery, M.A. Challenges of Drug-Facilitated Sexual Assault. Forensic Science Review, Volume 22, Number 1 (2010).
  24. LeBeau, M.A. and Montgomery, M.A. The Frequency of Drug-Facilitated Sexual Assault Investigations. Forensic Science Review, Volume 22, Number 1 (2010).
  25. Marinetti, L. and LeBeau, M.A. The Use of GHB and Analogs to Facilitate Sexual Assault. Forensic Science Review, Volume 22, Number 1 (2010).
  26. LeBeau, M.A. Laboratory Management of Drug-Facilitated Sexual Assault Cases. Forensic Science Review, Volume 22, Number 1 (2010).
  27. LeBeau, M.A., Montgomery, M.A., Brewer, J. The Role of Variations in Growth Rate and Sample Collection on Interpreting Results of Segmental Analyses of Hair. Forensic Science International. Volume 210, Issue 1 (2011). https://doi.org/10.1016/j.forsciint.2011.02.015
  28. Kaplan-Sandquist, K., LeBeau, M.A., and Miller, M.L. Chemical Analysis of Pharmaceuticals and Explosives in Fingermarks using Matrix-Assisted Laser Desorption Ionization/Time-of-Flight Mass Spectrometry. Forensic Science International, Vol 234, (2014). https://doi.org/10.1016/j.forsciint.2013.11.016
  29. Kaplan-Sandquist, K., LeBeau, M.A., and Miller, M.L. Evaluation of Four Fingerprint Development Methods for Touch Chemistry Using Matrix-Assisted Laser Desorption Ionization/Time-of-Flight Mass Spectrometry. Journal of Forensic Sciences, Volume 60, Issue 3, (2015). https://doi.org/10.1111/1556-4029.12718
  30. Jagerdeo, E., Montgomery, M.A., and LeBeau, M.A. An Improved Method for the Analysis of GHB in Human Hair by Liquid Chromatography Tandem Mass Spectrometry. Journal of Analytical Toxicology, Volume 39, Issue 2 (2015). https://doi.org/10.1093/jat/bku130
  31. Lloyd, EW., Thomas, JL., Donnelly, CC., Montgomery, MA., Karas, RK, LeBeau, MA., Miller, ML. Evaluating Endogenous GHB Variation in Hair with a Synthetic Hair Matrix. Journal of Analytical Toxicology, Volume 44, Issue 4 (2020). https://doi.org/10.1093/jat/bkz095
  32. Thomas, JL., Strickland, EC., Lloyd, EW., Donnelly, CC., Rankoth, A., Pieczonka, SM., Colpoys, C., Smith, MA., LeBeau, MA., Montgomery, MA., Karas, RP., Peters, EM., Miller, ML. Endogenous GHB in Segmented Hair Part 1: Inter-individual Variation for Group Comparisons. Journal of Analytical Toxicology, Volume 44, Issue 6 (2020). https://doi.org/10.1093/jat/bkaa080
  33. Strickland, EC., Thomas, JL., Lloyd, EW., Smith, MA., LeBeau, MA., Montgomery, MA., Karas, RP., Peters, EM., Miller, ML. Endogenous GHB in Segmented Hair Part 2: Intra-individual Variation for Exogenous Discrimination. Journal of Analytical Toxicology, Volume 44, Issue 7 (2020). https://doi.org/10.1093/jat/bkaa086
  34. Kustera, C., LeBeau, M., Sharma, S., Arroyo, L. Recent Trends in the Analysis of GHB in Hair. Journal of Analytical Toxicology, Published Online: July 17, 2025 https://doi.org/10.1093/jat/bkaf069

 

Letters to the Editor

  1. LeBeau, M., Montgomery, M., Jufer, R., and Miller, M. Elevated GHB in Citrate Buffered Blood. Journal of Analytical Toxicology, Volume 24, 2000. https://doi.org/10.1093/jat/24.5.383
  2. LeBeau, M.A. and Quenzer, C.F. Succinylmonocholine Identified in Negative Control Tissues, Journal of Analytical Toxicology, Volume 27, 2003. https://doi.org/10.1093/jat/27.8.600
  3. LeBeau, M.A. and Montgomery, M.A. Considerations on the Utility of Hair Analysis for Cocaine. Journal of Analytical Toxicology, Volume 33, 2009. https://doi.org/10.1093/jat/33.6.343
  4. LeBeau, M.A. and Montgomery, M.A. Comments on “Gamma-Hydroxybutyrate in Urine and Serum: Additional Data Supporting Current Cut-Off Recommendations.” Forensic Science International, Volume 207, Issue 1 (2011). https://doi.org/10.1016/j.forsciint.2010.09.023
  5. Montgomery, M., LeBeau, M., and Morris-Kukoski, C. New Hair Testing Conclusions. Journal of Analytical Toxicology, Volume 41 (2017). https://doi.org/10.1093/jat/bkw116
  6. LeBeau, MA and Limoges, JF. Letter to the Editor: Call for a Scientific Consensus Regarding the Application of Retrograde Extrapolation to Determine Blood Alcohol Content in DUI Cases. Journal of Forensic Sciences, Volume 64, Issue 1 (2019). https://doi.org/10.1111/1556-4029.13928
  7. LeBeau, MA. Letter to the Editor: ANSI/ASB Standard 036 for Method Validation in Forensic Toxicology has Replaced SWGTOX’s Version. Journal of Analytical Toxicology, Volume 44, Issue 4, May 2020. Published Feb 24, 2020 https://doi.org/10.1093/jat/bkz115
  8. Drummer, OH., Gerostamoulos, D., LeBeau, MA., Pragst, F. Letter to the Editor: Concerns on the Misinterpretation of Very Low Drug Concentrations in Hair. Journal of Analytical Toxicology. Published Jul 23, 2020 https://doi.org/10.1093/jat/bkaa078
  9. LeBeau, M.A., Harper, C.E., Johnson, R.D., Kahl, J.H., Reidy, L., Letter to the Editor: ANSI/ASB Standards 119, 120 and 121 Set Minimum Analytical Scope and Sensitivity for Subdisciplines of Forensic Toxicology. Journal of Analytical Toxicology. Published Dec 2, 2021 https://doi.org/10.1093/jat/bkab120
  10. LeBeau, M.A. and Limoges, J.F. Letter to the Editor: Answering the Call for a Scientific Consensus Regarding the Application of Retrograde Extrapolation to Determine Blood Alcohol Content in DUI Cases. Journal of Forensic Sciences, September 2024 https://doi.org/10.1111/1556-4029.15582

Books and Book Chapters

  1. Drug-Facilitated Sexual Assault: A Forensic Handbook. Marc A. LeBeau and Ashraf Mozayani, Eds. (2001), Academic Press: London.
  2. LeBeau, Marc "Gamma-Hydroxybutyric Acid (GHB)" in Principles of Forensic Toxicology. Barry Levine, Ed., 2nd edition, (2006), AACC Press, Washington, DC.
  3. LeBeau, Marc "Drug-Facilitated Sexual Assault" in Wiley Encyclopedia of Forensic Science, Allan Jamieson and Andre Moenssens, Eds., John Wiley and Sons, Ltd., 2009.
  4. LeBeau, Marc "Gamma-Hydroxybutyric Acid (GHB)" in Principles of Forensic Toxicology. Barry Levine, Ed., 3rd edition, (2010), AACC Press, Washington, DC.
  5. LeBeau, Marc "Drug-Facilitated Sexual Assault" in Medical Response to Adult Sexuality: A Resource for Clinicians and Other Professionals, Linda Ledray, Ann W. Burgess, and Angelo P. Giardino, Eds., STM Learning, Inc., 2010.
  6. LeBeau, Marc. A. "A Simplified Approach to Measurement Uncertainty" in Clarke's Analysis of Drugs and Poisons, 4th edition, Anthony C. Moffat, M. David Osselton, and Brian Widdop, Eds., Pharmaceutical Press, 2011.
  7. LeBeau, Marc "Gamma-Hydroxybutyric Acid (GHB)" in Principles of Forensic Toxicology. Barry Levine, Ed., 4th edition, (2013), AACC Press, Washington, DC.
  8. LeBeau, Marc and Montgomery, Madeline "Drug-Facilitated Crimes" in Principles of Forensic Toxicology. Barry Levine and Sarah Kerrigan, Eds., 5th edition, (2020), Springer, Cham, Switzerland.
  9. Levine, Barry and LeBeau, Marc "Miscellaneous Central Nervous System Depressants" in Principles of Forensic Toxicology. Barry Levine and Sarah Kerrigan, Eds., 5th edition, (2020), Springer, Cham, Switzerland.

Significant Contributions Towards Forensic Science Standards of Practice

  1. SWGDRUG Recommendations for Education and Training, Quality Assurance, and Methods of Analysis, U.S. Department of Justice, Drug Enforcement Administration, 2001.
  2. Guidelines for the Forensic Analysis of Drugs Facilitating Sexual Assault and Other Criminal Acts. United Nations Office on Crimes and Drugs. 2011.
  3. SWGTOX Standard Practices for Method Validation in Forensic Toxicology. Journal of Analytical Toxicology, Vol 37, Issue 7, Sep 2013, https://doi.org/10.1093/jat/bkt054
  4. ANSI/ASB Standard 017, Standard Practices for Measurement Traceability in Forensic Toxicology, First Edition, 2018.
  5. ANSI/ASB Standard 017, Standard Practices for Metrological Traceability in Forensic Toxicology, Second Edition, 2025.
  6. ANSI/ASB Standard 036, Standard Practices for Method Validation in Forensic Toxicology, First Edition, 2019.
  7. ANSI/ASB Best Practice Recommendation 037, Guidelines for Opinions and Testimony in Forensic Toxicology, First Edition, 2019.
  8. ANSI/ASB Standard 053, Standard for Report Content in Forensic Toxicology, First Edition, 2020.
  9. ANSI/ASB Standard 054, Standard for a Quality Control Program in Forensic Toxicology Laboratories, First Edition, 2021.
  10. ANSI/ASB Standard 055, Standard for Breath Alcohol Measuring Instrument Calibration, First Edition, 2024.
  11. ANSI/ASB Standard 056, Standard for Evaluation of Measurement Uncertainty in Forensic Toxicology, First Edition, 2025.
  12. ANSI/ASB Standard 098, Standard for Mass Spectral Analysis in Forensic Toxicology, First Edition, 2023.
  13. ANSI/ASB Standard 113, Standard for Identification Criteria in Forensic Toxicology, First Edition, 2023.
  14. ANSI/ASB Standard 119, Standard for the Analytical Scope and Sensitivity of Forensic Toxicological Testing of Blood in Medicolegal Death Investigations, First Edition, 2021.
  15. ANSI/ASB Standard 120, Standard for the Analytical Scope and Sensitivity of Forensic Toxicological Testing of Blood in Impaired Driving Investigations, First Edition, 2021.
  16. ANSI/ASB Standard 121, Standard for the Analytical Scope and Sensitivity of Forensic Toxicological Testing of Urine in Drug-Facilitated Crime Investigations, First Edition, 2021.
  17. ANSI/ASB Best Practice Recommendation 122, Best Practice Recommendation for Performing Alcohol Calculations in Forensic Toxicology, First Edition, 2024
  18. ANSI/ASB Standard 152, Standard for Minimum Content Requirements of Forensic Toxicology Procedures, First Edition, 2021.
  19. ANSI/ASB Standard 153, Standard Practices for Proficiency Testing for Forensic Toxicology Laboratories and Breath Alcohol Programs, First Edition, 2023.
  20. ANSI/ASB Standard 156, Best Practice Recommendations for Specimen Collection and Preservation for Forensic Toxicology, First Edition, 2023.
  21. ANSI/ASB Technical Report 208, Forensic Toxicology: Terms and Definitions, First Edition, 2025.

Honors and Awards

  • Federal Bureau of Investigation. FBI Director’s Award for Outstanding Scientific Advancement (2004)
  • Institute of Environmental Science and Research (ESR) 2007 International Fellow (2007)
  • End Violence Against Women International Visionary Award (2008)
  • Peace Corps Office of Inspector General. Outstanding Support of the Criminal Investigative Mission (2008)
  • American Academy of Forensic Sciences, Toxicology Section, Alexander O. Gettler Award (2015)
  • Federal Bureau of Investigation. FBI Director’s Award for Outstanding Scientific Advancement (2020)
  • American Academy of Forensic Sciences, Toxicology Section, Rolla Harger Award (2023)

Professional Organizations and Associations

  • American Academy of the Forensic Sciences (AAFS); Fellow
  • The International Association of Forensic Toxicologists (TIAFT); Member
  • Society of Forensic Toxicologists (SOFT); Full Member
  • ASTM International; Member